Corticosteroids enhance the capacity of macrophages to induce Th2 cytokine synthesis in CD4+ lymphocytes by inhibiting IL-12 production. [electronic resource]
Producer: 19980318Description: 2231-7 p. digitalISSN:- 0022-1767
- Adjuvants, Immunologic -- administration & dosage
- Animals
- Antigen-Presenting Cells -- drug effects
- CD4-Positive T-Lymphocytes -- metabolism
- Cell Adhesion -- drug effects
- Cells, Cultured
- Cytokines -- biosynthesis
- Dexamethasone -- administration & dosage
- Injections, Intraperitoneal
- Interferon Inducers -- antagonists & inhibitors
- Interferon-gamma -- biosynthesis
- Interleukin-12 -- antagonists & inhibitors
- Interleukin-4 -- antagonists & inhibitors
- Macrophages -- drug effects
- Mice
- Mice, Inbred BALB C
- Mice, Inbred DBA
- Spleen -- cytology
- Th2 Cells -- metabolism
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Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.
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