An Sp1-binding silencer element is a critical negative regulator of the megakaryocyte-specific alphaIIb gene. [electronic resource]
Producer: 19980407Description: 5716-26 p. digitalISSN:- 0021-9258
- Animals
- Base Sequence
- Binding Sites -- genetics
- Cell Line
- DNA-Binding Proteins -- analysis
- Gene Expression Regulation, Developmental -- genetics
- Genes, Reporter
- Humans
- Megakaryocytes -- physiology
- Molecular Sequence Data
- Nuclear Proteins -- analysis
- Platelet Glycoprotein GPIIb-IIIa Complex -- genetics
- Point Mutation -- genetics
- Promoter Regions, Genetic -- genetics
- Rats
- Recombinant Proteins -- genetics
- Sequence Deletion -- genetics
- Sp1 Transcription Factor -- genetics
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
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