ONO-5046, an elastase inhibitor, attenuates liver mitochondrial dysfunction after endotoxin. [electronic resource]
Producer: 19980128Description: 138-41 p. digitalISSN:- 0090-3493
- Adenosine Diphosphate -- metabolism
- Animals
- Blood Pressure -- drug effects
- Chemical and Drug Induced Liver Injury
- Dose-Response Relationship, Drug
- Escherichia coli
- Glycine -- analogs & derivatives
- Guinea Pigs
- Ketone Bodies -- metabolism
- Leukocyte Elastase -- antagonists & inhibitors
- Lipopolysaccharides -- toxicity
- Liver Diseases -- enzymology
- Male
- Mitochondria, Liver -- drug effects
- Oxygen -- metabolism
- Phosphorylation
- Respiration -- physiology
- Serine Proteinase Inhibitors -- pharmacology
- Sulfonamides -- pharmacology
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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