Estrogens stabilize mitochondrial function and protect neural cells against the pro-apoptotic action of mutant presenilin-1. [electronic resource]
Producer: 19980217Description: 3817-21 p. digitalISSN:- 0959-4965
- Amino Acid Substitution
- Amyloid beta-Peptides -- pharmacology
- Animals
- Apoptosis -- drug effects
- Cell Differentiation
- Corticosterone -- pharmacology
- Energy Metabolism
- Estradiol -- pharmacology
- Estriol -- pharmacology
- Growth Substances -- pharmacology
- Humans
- Intracellular Membranes -- drug effects
- Membrane Potentials -- drug effects
- Membrane Proteins -- biosynthesis
- Mitochondria -- drug effects
- Oxidative Stress
- PC12 Cells
- Peptide Fragments -- pharmacology
- Point Mutation
- Presenilin-1
- Rats
- Reactive Oxygen Species
- Recombinant Proteins -- biosynthesis
- Transfection
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Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.
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