Human testis-determining factor SRY binds to the major DNA adduct of cisplatin and a putative target sequence with comparable affinities. [electronic resource]
Producer: 19980202Description: 352-62 p. digitalISSN:- 0006-2960
- Binding, Competitive -- genetics
- Cisplatin -- antagonists & inhibitors
- DNA -- metabolism
- DNA Adducts -- antagonists & inhibitors
- DNA Probes -- metabolism
- DNA Repair -- drug effects
- DNA-Binding Proteins -- isolation & purification
- Deoxyguanine Nucleotides -- metabolism
- High Mobility Group Proteins -- isolation & purification
- Humans
- Male
- Nuclear Proteins
- Peptide Fragments -- metabolism
- Protein Binding -- drug effects
- Protein Structure, Tertiary
- Recombinant Proteins -- isolation & purification
- Sex-Determining Region Y Protein
- Testis -- metabolism
- Transcription Factors
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Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
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