The tumor suppressor gene Smad4/Dpc4 is required for gastrulation and later for anterior development of the mouse embryo. [electronic resource]
Producer: 19980213Description: 107-19 p. digitalISSN:- 0890-9369
- Alleles
- Animals
- Basic Helix-Loop-Helix Leucine Zipper Transcription Factors
- Carcinogenicity Tests
- Cell Line
- DNA-Binding Proteins -- metabolism
- Embryonic and Fetal Development -- genetics
- Endoderm -- physiology
- Female
- Fetal Proteins
- Gastrula -- physiology
- Gene Deletion
- Genes, Tumor Suppressor
- Hepatocyte Nuclear Factor 4
- Heterozygote
- Homozygote
- Male
- Mesoderm -- physiology
- Mice
- Mice, Inbred C57BL
- Phosphoproteins -- metabolism
- Smad4 Protein
- Stem Cells -- cytology
- T-Box Domain Proteins
- Trans-Activators -- biosynthesis
- Transcription Factors -- metabolism
- Brachyury Protein
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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