Resistance to nevirapine of HIV-1 reverse transcriptase mutants: loss of stabilizing interactions and thermodynamic or steric barriers are induced by different single amino acid substitutions. [electronic resource]
Producer: 19980130Description: 738-47 p. digitalISSN:- 0022-2836
- Anti-HIV Agents -- metabolism
- Drug Resistance, Microbial
- HIV Reverse Transcriptase -- antagonists & inhibitors
- HIV-1 -- drug effects
- Humans
- Kinetics
- Mutation -- physiology
- Nevirapine -- metabolism
- Protein Binding
- Recombinant Fusion Proteins
- Reverse Transcriptase Inhibitors -- metabolism
- Thermodynamics
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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