An apoptosis-inducing genotoxin differentiates heterozygotic carriers for Werner helicase mutations from wild-type and homozygous mutants. [electronic resource]
Producer: 19980108Description: 121-5 p. digitalISSN:- 0340-6717
- 4-Nitroquinoline-1-oxide -- pharmacology
- Apoptosis -- genetics
- B-Lymphocytes -- drug effects
- Cell Line
- DNA Helicases -- genetics
- Dose-Response Relationship, Drug
- Exodeoxyribonucleases
- Heterozygote
- Homozygote
- Humans
- Mutagens -- pharmacology
- Mutation
- Phenotype
- RecQ Helicases
- Werner Syndrome -- enzymology
- Werner Syndrome Helicase
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Publication Type: Comparative Study; Journal Article; Research Support, U.S. Gov't, P.H.S.
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