Sialyl-Lewis(x) sequence 6-O-sulfated at N-acetylglucosamine rather than at galactose is the preferred ligand for L-selectin and de-N-acetylation of the sialic acid enhances the binding strength. [electronic resource]
Producer: 19980113Description: 748-51 p. digitalISSN:- 0006-291X
- Acetylation
- Acetylglucosamine -- chemistry
- Carbohydrate Sequence
- Ceramides -- chemistry
- Endothelium, Vascular -- chemistry
- Galactose -- chemistry
- L-Selectin -- metabolism
- Ligands
- Mass Spectrometry
- Molecular Sequence Data
- N-Acetylneuraminic Acid -- chemistry
- Oligosaccharides -- analysis
- Protein Binding
- Recombinant Proteins -- metabolism
- Sialyl Lewis X Antigen
- Sulfates -- chemistry
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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