Opposite modulation of opiate withdrawal behaviors on microinfusion of a protein kinase A inhibitor versus activator into the locus coeruleus or periaqueductal gray. [electronic resource]
Producer: 19971120Description: 8520-7 p. digitalISSN:- 0270-6474
- Amygdala -- drug effects
- Animals
- Behavior, Animal -- drug effects
- Cyclic AMP -- analogs & derivatives
- Cyclic AMP-Dependent Protein Kinases -- antagonists & inhibitors
- Enzyme Inhibitors -- administration & dosage
- Infusions, Parenteral
- Locus Coeruleus -- drug effects
- Male
- Morphine Dependence -- complications
- Motor Activity -- drug effects
- Naloxone -- toxicity
- Narcotic Antagonists -- toxicity
- Nerve Tissue Proteins -- antagonists & inhibitors
- Periaqueductal Gray -- drug effects
- Phosphorylation -- drug effects
- Protein Processing, Post-Translational -- drug effects
- Rats
- Rats, Sprague-Dawley
- Second Messenger Systems -- drug effects
- Stereotyped Behavior -- drug effects
- Substance Withdrawal Syndrome -- etiology
- Thionucleotides -- pharmacology
- Tyrosine 3-Monooxygenase -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
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