A region of the beta subunit of the interferon alpha receptor different from box 1 interacts with Jak1 and is sufficient to activate the Jak-Stat pathway and induce an antiviral state. [electronic resource]
Producer: 19971117Description: 26388-93 p. digitalISSN:- 0021-9258
- Animals
- Cell Line
- Cytoplasm -- metabolism
- Glutathione Transferase -- genetics
- Humans
- Interferon-alpha -- metabolism
- Janus Kinase 1
- Mice
- Protein Binding
- Protein-Tyrosine Kinases -- metabolism
- Receptor, Interferon alpha-beta
- Receptors, Interferon -- chemistry
- Recombinant Fusion Proteins -- chemistry
- Transfection
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Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.
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