Fluvoxamine inhibits the CYP2C19-catalyzed bioactivation of chloroguanide. [electronic resource]
Producer: 19971113Description: 279-86 p. digitalISSN:- 0009-9236
- Administration, Oral
- Adult
- Antimetabolites -- pharmacokinetics
- Aryl Hydrocarbon Hydroxylases
- Biguanides -- blood
- Biotransformation
- Cross-Over Studies
- Cytochrome P-450 CYP2C19
- Cytochrome P-450 CYP3A
- Cytochrome P-450 Enzyme Inhibitors
- Cytochrome P-450 Enzyme System -- metabolism
- Drug Interactions
- Fluvoxamine -- pharmacology
- Folic Acid Antagonists -- blood
- Humans
- Male
- Mephenytoin -- metabolism
- Mixed Function Oxygenases -- antagonists & inhibitors
- Proguanil -- blood
- Selective Serotonin Reuptake Inhibitors -- pharmacology
- Triazines -- blood
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Publication Type: Clinical Trial; Comparative Study; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
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