Genetic polymorphism of the CYP2C subfamily and its effect on the pharmacokinetics of phenytoin in Japanese patients with epilepsy. [electronic resource]
Producer: 19971113Description: 287-92 p. digitalISSN:- 0009-9236
- Adolescent
- Adult
- Anticonvulsants -- pharmacokinetics
- Aryl Hydrocarbon Hydroxylases
- Bayes Theorem
- Child
- Child, Preschool
- Cytochrome P-450 CYP2C19
- Cytochrome P-450 CYP2C9
- Cytochrome P-450 Enzyme System -- chemistry
- Epilepsy -- drug therapy
- Female
- Gene Expression Regulation, Enzymologic -- genetics
- Genotype
- Heterozygote
- Humans
- Infant
- Japan
- Male
- Mixed Function Oxygenases -- chemistry
- Mutation -- genetics
- Phenytoin -- blood
- Polymerase Chain Reaction
- Polymorphism, Genetic
- Steroid 16-alpha-Hydroxylase
- Steroid Hydroxylases -- chemistry
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Publication Type: Clinical Trial; Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
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