Ionizing radiation and teniposide increase p21(waf1/cip1) and promote Rb dephosphorylation but fail to suppress E2F activity in MCF-7 breast tumor cells. [electronic resource]
Producer: 19971002Description: 373-9 p. digitalISSN:- 0026-895X
- Antineoplastic Agents, Phytogenic -- pharmacology
- Binding Sites
- Breast Neoplasms -- metabolism
- Carrier Proteins
- Cell Cycle -- drug effects
- Cell Cycle Proteins
- Cyclin-Dependent Kinase Inhibitor p21
- Cyclins -- biosynthesis
- DNA-Binding Proteins
- E2F Transcription Factors
- Humans
- Luciferases -- genetics
- Phosphorylation
- Plasmids
- Retinoblastoma Protein -- drug effects
- Retinoblastoma-Binding Protein 1
- Signal Transduction -- physiology
- Teniposide -- pharmacology
- Transcription Factor DP1
- Transcription Factors -- drug effects
- Transfection
- Tumor Cells, Cultured -- drug effects
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Publication Type: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S.
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