Mechanism of action of fotemustine, a new chloroethylnitrosourea anticancer agent: evidence for the formation of two DNA-reactive intermediates contributing to cytotoxicity. [electronic resource]
Producer: 19970917Description: 10646-54 p. digitalISSN:- 0006-2960
- Antineoplastic Agents -- metabolism
- Cell Survival -- drug effects
- DNA Adducts -- metabolism
- DNA Methylation -- drug effects
- DNA Repair -- drug effects
- Dose-Response Relationship, Drug
- Drug Stability
- Guanine -- metabolism
- HeLa Cells
- Humans
- Mass Spectrometry
- Melanoma
- Nitrosourea Compounds -- metabolism
- Organophosphorus Compounds -- metabolism
- Tumor Cells, Cultured
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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