Regulation of the oncogenic activity of BCR-ABL by a tightly bound substrate protein RIN1. [electronic resource]
Producer: 19970728Description: 773-82 p. digitalISSN:- 1074-7613
- Adaptor Proteins, Signal Transducing
- Animals
- Carrier Proteins -- physiology
- Cell Division
- Cell Transformation, Neoplastic -- genetics
- Fusion Proteins, bcr-abl -- metabolism
- GRB2 Adaptor Protein
- Hematopoiesis
- Humans
- Intracellular Signaling Peptides and Proteins
- Leukemia, Experimental -- genetics
- Macromolecular Substances
- Mice
- Phosphorylation
- Phosphotyrosine -- metabolism
- Protein Binding
- Proteins -- metabolism
- Signal Transduction
- Structure-Activity Relationship
- Survival Analysis
- Tumor Cells, Cultured
- rab GTP-Binding Proteins
- src Homology Domains
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
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