High dose IL-2-activated murine natural killer (A-NK) cells accumulate glycogen and granules, lose cytotoxicity, and alter target cell interaction in vitro. [electronic resource]
Producer: 19970721Description: 623-36 p. digitalISSN:- 0300-9475
- Animals
- Cell Adhesion
- Cell Communication -- drug effects
- Cell Compartmentation
- Cell Division -- immunology
- Cell Nucleus -- ultrastructure
- Cytoplasmic Granules -- immunology
- Cytotoxicity, Immunologic -- drug effects
- Dose-Response Relationship, Immunologic
- Glycogen -- biosynthesis
- Humans
- Immunophenotyping
- Inclusion Bodies -- ultrastructure
- Interleukin-2 -- pharmacology
- Killer Cells, Lymphokine-Activated -- immunology
- Lipid Metabolism
- Lymphocyte Activation -- drug effects
- Lymphoma
- Lysosomes -- ultrastructure
- Male
- Melanoma, Experimental
- Mice
- Mice, Inbred C57BL
- Proteoglycans -- metabolism
- Time Factors
- Tumor Cells, Cultured
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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