Interaction of CTLA-4 with the clathrin-associated protein AP50 results in ligand-independent endocytosis that limits cell surface expression. [electronic resource]
Producer: 19970714Description: 144-51 p. digitalISSN:- 0022-1767
- Abatacept
- Adaptor Protein Complex 2
- Adaptor Protein Complex mu Subunits
- Adaptor Proteins, Vesicular Transport
- Amino Acid Sequence
- Antigens, CD
- Antigens, Differentiation -- genetics
- CTLA-4 Antigen
- Endocytosis -- immunology
- Humans
- Immunoconjugates
- Jurkat Cells
- Lymphocyte Activation -- immunology
- Molecular Sequence Data
- Mutation
- Nerve Tissue Proteins -- immunology
- Phosphoproteins -- immunology
- Receptor Aggregation
- Signal Transduction -- immunology
- T-Lymphocytes -- immunology
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Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.
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