The immunosuppressive metabolite of leflunomide, A77 1726, affects murine T cells through two biochemical mechanisms. [electronic resource]
Producer: 19970714Description: 22-7 p. digitalISSN:- 0022-1767
- Aniline Compounds -- pharmacology
- Animals
- Cell Division -- drug effects
- Cell Line
- Crotonates
- Hydroxybutyrates -- pharmacology
- Immunosuppressive Agents -- pharmacology
- Janus Kinase 1
- Janus Kinase 3
- Lymphocyte Activation -- drug effects
- Lymphocyte Specific Protein Tyrosine Kinase p56(lck)
- Mice
- Nitriles
- Protein-Tyrosine Kinases -- immunology
- T-Lymphocytes, Cytotoxic -- cytology
- Toluidines
- src-Family Kinases -- immunology
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
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