Efficacy, pharmacokinetics, and in vivo antiviral activity of UC781, a highly potent, orally bioavailable nonnucleoside reverse transcriptase inhibitor of HIV type 1. [electronic resource]
Producer: 19970620Description: 789-96 p. digitalISSN:- 0889-2229
- Administration, Oral
- Anilides -- pharmacokinetics
- Animals
- Anti-HIV Agents -- pharmacokinetics
- Biological Availability
- Furans -- pharmacokinetics
- HIV Core Protein p24 -- analysis
- HIV Reverse Transcriptase -- antagonists & inhibitors
- HIV-1 -- drug effects
- HIV-2 -- drug effects
- Humans
- Male
- Metabolic Clearance Rate
- Mice
- Mice, Inbred Strains
- Microbial Sensitivity Tests
- Point Mutation
- Reverse Transcriptase Inhibitors -- pharmacokinetics
- Thioamides
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
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