Thrombopoietin directly and potently stimulates multilineage growth and progenitor cell expansion from primitive (CD34+ CD38-) human bone marrow progenitor cells: distinct and key interactions with the ligands for c-kit and flt3, and inhibitory effects of TGF-beta and TNF-alpha. [electronic resource]
Producer: 19970619Description: 5169-77 p. digitalISSN:- 0022-1767
- Animals
- Antigens, CD34
- Bone Marrow -- metabolism
- Bone Marrow Cells
- Cell Differentiation -- drug effects
- Cell Lineage -- drug effects
- Cells, Cultured
- Hematopoietic Stem Cells -- cytology
- Humans
- Mice
- Proto-Oncogene Proteins -- metabolism
- Proto-Oncogene Proteins c-kit -- metabolism
- Receptor Protein-Tyrosine Kinases -- metabolism
- Recombinant Proteins -- pharmacology
- Thrombopoietin -- pharmacology
- Transforming Growth Factor beta -- metabolism
- Tumor Necrosis Factor-alpha -- metabolism
- fms-Like Tyrosine Kinase 3
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Publication Type: Journal Article
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