Botulinum neurotoxin B inhibits insulin-stimulated glucose uptake into 3T3-L1 adipocytes and cleaves cellubrevin unlike type A toxin which failed to proteolyze the SNAP-23 present. [electronic resource]
Producer: 19970609Description: 5719-28 p. digitalISSN:- 0006-2960
- 3T3 Cells
- Adipocytes -- drug effects
- Animals
- Antigens, Surface -- metabolism
- Botulinum Toxins -- pharmacology
- Botulinum Toxins, Type A -- pharmacology
- Carrier Proteins -- drug effects
- Cell Membrane -- chemistry
- Endopeptidases
- Glucose -- antagonists & inhibitors
- Glucose Transporter Type 1
- Glucose Transporter Type 4
- Hydrolysis
- Insulin -- pharmacology
- Membrane Proteins -- antagonists & inhibitors
- Mice
- Monosaccharide Transport Proteins -- antagonists & inhibitors
- Muscle Proteins
- Nerve Tissue Proteins -- metabolism
- Qb-SNARE Proteins
- Qc-SNARE Proteins
- R-SNARE Proteins
- Subcellular Fractions -- metabolism
- Synaptosomal-Associated Protein 25
- Syntaxin 1
- Vesicle-Associated Membrane Protein 3
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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