Treatment with depleting CD4 monoclonal antibody results in a preferential loss of circulating naive T cells but does not affect IFN-gamma secreting TH1 cells in humans. [electronic resource]
Producer: 19970624Description: 2225-31 p. digitalISSN:- 0021-9738
- Adult
- Antibodies, Monoclonal -- therapeutic use
- CD4 Antigens -- immunology
- CD4-Positive T-Lymphocytes -- immunology
- CD8-Positive T-Lymphocytes -- immunology
- Double-Blind Method
- Female
- Humans
- Interferon-gamma -- biosynthesis
- Interleukin-4 -- biosynthesis
- Leukocyte Common Antigens -- immunology
- Lymphocyte Depletion
- Male
- Middle Aged
- Multiple Sclerosis -- immunology
- T-Lymphocyte Subsets -- immunology
- Th1 Cells -- immunology
- Th2 Cells -- immunology
- fas Receptor -- immunology
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Publication Type: Clinical Trial; Clinical Trial, Phase II; Journal Article; Multicenter Study; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
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