A prevalent amino acid polymorphism at codon 98 in the hepatocyte nuclear factor-1alpha gene is associated with reduced serum C-peptide and insulin responses to an oral glucose challenge. [electronic resource]
Producer: 19970528Description: 912-6 p. digitalISSN:- 0012-1797
- Administration, Oral
- Adult
- Aged
- Alanine -- genetics
- Amino Acids -- genetics
- Asparagine -- genetics
- C-Peptide -- blood
- Codon
- DNA-Binding Proteins
- Female
- Glucose -- administration & dosage
- Glucose Tolerance Test
- Hepatocyte Nuclear Factor 1
- Hepatocyte Nuclear Factor 1-alpha
- Hepatocyte Nuclear Factor 1-beta
- Humans
- Insulin -- metabolism
- Insulin Secretion
- Isoleucine -- genetics
- Leucine -- genetics
- Male
- Middle Aged
- Nuclear Proteins
- Polymorphism, Genetic
- Serine -- genetics
- Transcription Factors -- genetics
- Valine -- genetics
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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