An ovalbumin-IL-12 fusion protein is more effective than ovalbumin plus free recombinant IL-12 in inducing a T helper cell type 1-dominated immune response and inhibiting antigen-specific IgE production. [electronic resource]
Producer: 19970519Description: 4137-44 p. digitalISSN:- 0022-1767
- Animals
- Antigens -- administration & dosage
- Female
- Hypersensitivity -- immunology
- Immunoglobulin E -- biosynthesis
- Immunoglobulin G -- biosynthesis
- Interferon-gamma -- biosynthesis
- Interleukin-12 -- administration & dosage
- Lymphocyte Activation
- Mice
- Mice, Inbred BALB C
- Ovalbumin -- chemistry
- Recombinant Fusion Proteins -- immunology
- Th1 Cells -- immunology
- Th2 Cells -- immunology
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
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