Insertion of the adenoviral E3 region into a recombinant viral vector prevents antiviral humoral and cellular immune responses and permits long-term gene expression. [electronic resource]
Producer: 19970424Description: 2587-92 p. digitalISSN:- 0027-8424
- Adenoviridae
- Adenovirus E3 Proteins -- biosynthesis
- Animals
- Antibody Formation
- Bile -- metabolism
- Bilirubin -- analogs & derivatives
- Genetic Therapy -- methods
- Genetic Vectors
- Glucuronosyltransferase -- biosynthesis
- Humans
- Hyperbilirubinemia -- immunology
- Immunity, Cellular
- Inflammation
- Liver -- enzymology
- Rats
- Rats, Inbred Strains
- Time Factors
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Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.
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