Competitive and non-competitive NMDA antagonists block the development of antinociceptive tolerance to morphine, but not to selective mu or delta opioid agonists in mice. [electronic resource]
Producer: 19970424Description: 229-37 p. digitalISSN:- 0304-3959
- Analgesics, Opioid -- therapeutic use
- Animals
- Binding, Competitive
- Dizocilpine Maleate -- therapeutic use
- Drug Tolerance
- Enkephalin, Ala(2)-MePhe(4)-Gly(5)-
- Enkephalins -- therapeutic use
- Excitatory Amino Acid Antagonists -- therapeutic use
- Fentanyl -- therapeutic use
- Isoquinolines -- therapeutic use
- Male
- Mice
- Mice, Inbred ICR
- Morphine -- therapeutic use
- Oligopeptides -- therapeutic use
- Receptors, N-Methyl-D-Aspartate -- antagonists & inhibitors
- Receptors, Opioid, delta -- agonists
- Receptors, Opioid, mu -- agonists
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Publication Type: Comparative Study; Journal Article; Research Support, U.S. Gov't, P.H.S.
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