The antibipolar drug valproate mimics lithium in stimulating glutamate release and inositol 1,4,5-trisphosphate accumulation in brain cortex slices but not accumulation of inositol monophosphates and bisphosphates. [electronic resource]
Producer: 19970527Description: 4757-60 p. digitalISSN:- 0027-8424
- Animals
- Antidepressive Agents -- pharmacology
- Antimanic Agents -- pharmacology
- Bipolar Disorder -- drug therapy
- Cerebral Cortex -- drug effects
- Drug Interactions
- Glutamic Acid -- metabolism
- Inositol 1,4,5-Trisphosphate -- metabolism
- Inositol Phosphates -- metabolism
- Lithium -- pharmacology
- Male
- Mice
- Mice, Inbred ICR
- Molecular Mimicry
- Receptors, N-Methyl-D-Aspartate -- metabolism
- Valproic Acid -- pharmacology
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Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
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