Function of C3 in a humoral response: iC3b/C3dg bound to an immune complex generated with natural antibody and a primary antigen promotes antigen uptake and the expression of co-stimulatory molecules by all B cells, but only stimulates immunoglobulin synthesis by antigen-specific B cells. [electronic resource]
Producer: 19970505Description: 531-7 p. digitalISSN:- 0009-9104
- Antibodies, Monoclonal -- immunology
- Antibody Formation
- Antibody Specificity
- Antigen Presentation
- Antigen-Antibody Complex -- immunology
- B-Lymphocytes -- immunology
- Cells, Cultured
- Complement C3b -- immunology
- Complement C3d -- immunology
- Enzyme-Linked Immunosorbent Assay
- Hemocyanins -- immunology
- Humans
- Immunoglobulin G -- immunology
- Immunoglobulin M -- immunology
- Leukocytes, Mononuclear -- immunology
- Lymphocyte Activation
- Lymphocyte Function-Associated Antigen-1 -- immunology
- Receptors, Complement 3d -- immunology
- Receptors, IgG -- immunology
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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