A novel Met-to-Thr mutation in the YMDD motif of reverse transcriptase from feline immunodeficiency virus confers resistance to oxathiolane nucleosides. [electronic resource]
Producer: 19970318Description: 2357-62 p. digitalISSN:- 0022-538X
- Animals
- Antiviral Agents -- pharmacology
- Binding Sites
- Cats
- Cell Line
- Drug Resistance, Microbial -- genetics
- Emtricitabine -- analogs & derivatives
- Immunodeficiency Virus, Feline -- drug effects
- Lamivudine -- pharmacology
- Methionine
- Mutagenesis, Site-Directed
- RNA-Directed DNA Polymerase -- genetics
- Sequence Analysis, DNA
- Threonine
- Viral Plaque Assay
- Zalcitabine -- analogs & derivatives
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S.
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