Transcription mediated by NFAT is highly inducible in effector CD4+ T helper 2 (Th2) cells but not in Th1 cells. [electronic resource]
Producer: 19970314Description: 1522-34 p. digitalISSN:- 0270-7306
- Animals
- CD4-Positive T-Lymphocytes -- cytology
- Cell Differentiation
- Cell Extracts
- Cell Nucleus
- Cyclic AMP Response Element-Binding Protein -- metabolism
- DNA -- metabolism
- DNA-Binding Proteins -- physiology
- Gene Expression Regulation
- Humans
- Interleukin-4 -- biosynthesis
- Jurkat Cells
- Lymphocyte Activation
- Mice
- Mice, Transgenic
- NFATC Transcription Factors
- Nuclear Proteins
- Th1 Cells -- cytology
- Th2 Cells -- cytology
- Transcription Factor AP-1 -- metabolism
- Transcription Factors -- physiology
- Transcriptional Activation
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Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.
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