Reversal of P-glycoprotein is greatly reduced by the presence of plasma but can be monitored by an ex vivo clinical assay. [electronic resource]
Producer: 19970313Description: 678-86 p. digitalISSN:- 0959-4973
- ATP Binding Cassette Transporter, Subfamily B, Member 1 -- antagonists & inhibitors
- Animals
- Cyclosporine -- blood
- Daunorubicin -- metabolism
- Drug Screening Assays, Antitumor
- Humans
- Kidney -- metabolism
- Leukemia P388 -- drug therapy
- Mice
- Plasma
- Quinidine -- blood
- Verapamil -- pharmacology
- Vinblastine -- metabolism
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Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
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