Treatment of advanced CNS malignancies with the recombinant adenovirus H5.010RSVTK: a phase I trial. [electronic resource]
Producer: 19970116Description: 1465-82 p. digitalISSN:- 1043-0342
- Adenoviridae Infections -- drug therapy
- Adenoviruses, Human -- genetics
- Adult
- Aged
- Animals
- Antiviral Agents -- pharmacology
- Astrocytoma -- radiotherapy
- Brain Neoplasms -- radiotherapy
- Clinical Protocols
- Combined Modality Therapy
- Defective Viruses -- genetics
- Female
- Ganciclovir -- pharmacology
- Genetic Therapy
- Genetic Vectors -- administration & dosage
- Glioblastoma -- radiotherapy
- Humans
- Informed Consent
- Injections, Intralesional
- Male
- Mice
- Middle Aged
- Neoplasm Recurrence, Local -- therapy
- Neoplastic Stem Cells -- drug effects
- Palliative Care
- Patient Selection
- Primates
- Rats
- Recombinant Fusion Proteins -- antagonists & inhibitors
- Safety
- Simplexvirus -- genetics
- Thymidine Kinase -- antagonists & inhibitors
- Transfection
- Viral Proteins -- antagonists & inhibitors
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Publication Type: Clinical Trial; Clinical Trial, Phase I; Journal Article
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