Retroviral vector-mediated transfer of the galactocerebrosidase (GALC) cDNA leads to overexpression and transfer of GALC activity to neighboring cells. [electronic resource]
Producer: 19961101Description: 142-50 p. digitalISSN:- 1077-3150
- Animals
- Cells, Cultured
- DNA, Complementary -- analysis
- Fibroblasts -- pathology
- Galactosylceramidase -- biosynthesis
- Gene Transfer Techniques
- Genetic Vectors -- genetics
- Humans
- Leukodystrophy, Globoid Cell -- genetics
- Lysosomes -- enzymology
- Mutation
- RNA, Messenger -- analysis
- Rats
- Retroviridae -- genetics
- Transduction, Genetic
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
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