Cardiotoxic and drug interaction profile of the second generation antihistamines ebastine and terfenadine in an experimental animal model of torsade de pointes. [electronic resource]
Producer: 19970123Description: 159-63 p. digitalISSN:- 0004-4172
- Animals
- Butyrophenones -- toxicity
- Cytochrome P-450 CYP3A
- Cytochrome P-450 Enzyme System -- metabolism
- Drug Interactions
- Electrocardiography -- drug effects
- Guinea Pigs
- Heart Diseases -- chemically induced
- Histamine H1 Antagonists -- toxicity
- Ketoconazole -- pharmacology
- Liver -- enzymology
- Male
- Mixed Function Oxygenases -- metabolism
- Piperidines -- toxicity
- Terfenadine -- toxicity
- Torsades de Pointes -- chemically induced
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Publication Type: Journal Article
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