The p53-MDM2 interaction in a cancer-prone family, and the identification of a novel therapeutic target. [electronic resource]
Producer: 19960903Description: 429-34 p. digitalISSN:- 0284-186X
- Antineoplastic Agents -- chemical synthesis
- Breast Neoplasms -- drug therapy
- Carcinoma in Situ -- genetics
- Carcinoma, Ductal, Breast -- genetics
- Cell Division -- genetics
- Cyclin-Dependent Kinase Inhibitor p21
- Cyclins -- genetics
- Drug Design
- Enzyme Inhibitors -- metabolism
- Female
- Gene Expression Regulation, Neoplastic
- Genes, p53 -- genetics
- Humans
- Leiomyosarcoma -- genetics
- Neoplasm Proteins -- genetics
- Neoplasm Recurrence, Local -- genetics
- Neoplasms, Second Primary -- genetics
- Nuclear Proteins
- Phenotype
- Protein Binding
- Proto-Oncogene Proteins -- genetics
- Proto-Oncogene Proteins c-mdm2
- Proto-Oncogenes -- genetics
- Soft Tissue Neoplasms -- genetics
- Transcription, Genetic -- genetics
- Tumor Suppressor Protein p53 -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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