Design and synthesis of 6-chloro-3,4-dihydro-4-methyl-2H-1,4-benzoxazine-8-carboxamide derivatives as potent serotonin-3 (5-HT3) receptor antagonists. [electronic resource]
Producer: 19960822Description: 756-64 p. digitalISSN:- 0009-2363
- Animals
- Benzamides -- pharmacokinetics
- Binding, Competitive -- drug effects
- Blood Pressure -- drug effects
- Bridged Bicyclo Compounds, Heterocyclic -- pharmacokinetics
- Cerebral Cortex -- drug effects
- Granisetron -- metabolism
- Heart Rate -- drug effects
- In Vitro Techniques
- Male
- Oxazines -- chemical synthesis
- Rats
- Receptors, Serotonin -- drug effects
- Reflex -- drug effects
- Serotonin Antagonists -- chemical synthesis
- Stereoisomerism
- Structure-Activity Relationship
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Publication Type: Journal Article
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