The effect of 9-beta-D-arabinofuranosyl-2-fluoroadenine and 1-beta-D-arabinofuranosylcytosine on the cell cycle phase distribution, topoisomerase II level, mitoxantrone cytotoxicity, and DNA strand break production in K562 human leukemia cells. [electronic resource]
Producer: 19960725Description: 261-8 p. digitalISSN:- 0344-5704
- Antineoplastic Agents -- pharmacology
- Cell Cycle -- drug effects
- Cytarabine -- pharmacology
- DNA Damage -- drug effects
- DNA Topoisomerases, Type II -- metabolism
- Dose-Response Relationship, Drug
- Humans
- Immunoblotting
- Leukemia, Myeloid, Acute -- pathology
- Mitoxantrone -- toxicity
- Protein Binding -- drug effects
- Tumor Cells, Cultured -- drug effects
- Vidarabine -- analogs & derivatives
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
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