A nucleoside diphosphate kinase A (nm23-H1) serine 120-->glycine substitution in advanced stage neuroblastoma affects enzyme stability and alters protein-protein interaction. [electronic resource]
Producer: 19960705Description: 659-67 p. digitalISSN:- 0950-9232
- Base Sequence
- Cross-Linking Reagents
- DNA Primers
- Enzyme Stability
- Glutaral
- Glycine
- Hot Temperature
- Humans
- Isoenzymes -- chemistry
- Kinetics
- Molecular Sequence Data
- Monomeric GTP-Binding Proteins
- Mutagenesis, Site-Directed
- NM23 Nucleoside Diphosphate Kinases
- Neoplasm Staging
- Neuroblastoma -- enzymology
- Nucleoside-Diphosphate Kinase -- chemistry
- Point Mutation
- Polymerase Chain Reaction
- Protein Denaturation
- Recombinant Proteins -- chemistry
- Serine
- Thermodynamics
- Transcription Factors -- chemistry
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
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