TCR activation of ZAP70 is impaired in CD4+CD8+ thymocytes as a consequence of intrathymic interactions that diminish available p56lck. [electronic resource]
Producer: 19960703Description: 495-504 p. digitalISSN:- 1074-7613
- Animals
- Binding, Competitive -- immunology
- CD4 Antigens -- immunology
- CD8 Antigens -- immunology
- Cell Communication -- immunology
- Histocompatibility Antigens Class II -- metabolism
- Lymphocyte Specific Protein Tyrosine Kinase p56(lck)
- Mice
- Mice, Inbred C57BL
- Mice, Mutant Strains
- Protein-Tyrosine Kinases -- immunology
- Receptors, Antigen, T-Cell -- chemistry
- Signal Transduction -- immunology
- Structure-Activity Relationship
- T-Lymphocyte Subsets -- classification
- Thymus Gland -- cytology
- ZAP-70 Protein-Tyrosine Kinase
- src-Family Kinases -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
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