Inhibitors of the proteasome pathway interfere with induction of nitric oxide synthase in macrophages by blocking activation of transcription factor NF-kappa B. [electronic resource]
Producer: 19960618Description: 3308-12 p. digitalISSN:- 0027-8424
- Amino Acid Sequence
- Animals
- Arginine -- analogs & derivatives
- Base Sequence
- Calpain -- antagonists & inhibitors
- Cell Line
- Cycloheximide -- pharmacology
- Cysteine Endopeptidases -- metabolism
- DNA -- genetics
- Enzyme Induction -- drug effects
- Lipopolysaccharides -- pharmacology
- Macrophage Activation -- drug effects
- Macrophages, Alveolar -- drug effects
- Molecular Sequence Data
- Multienzyme Complexes -- metabolism
- NF-kappa B -- genetics
- Nitric Oxide Synthase -- biosynthesis
- Oligopeptides -- chemistry
- Protease Inhibitors -- pharmacology
- Proteasome Endopeptidase Complex
- RNA, Messenger -- genetics
- Rats
- omega-N-Methylarginine
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Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.
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