Angiotensin II-mediated hypertension in the rat increases vascular superoxide production via membrane NADH/NADPH oxidase activation. Contribution to alterations of vasomotor tone. [electronic resource]
Producer: 19960614Description: 1916-23 p. digitalISSN:- 0021-9738
- Acetylcholine -- pharmacology
- Angiotensin II -- pharmacology
- Animals
- Antihypertensive Agents -- pharmacology
- Aorta
- Arginine -- analogs & derivatives
- Biphenyl Compounds -- pharmacology
- Calcimycin -- pharmacology
- Endothelium, Vascular -- physiology
- Enzyme Activation
- Enzyme Inhibitors -- pharmacology
- Hypertension -- chemically induced
- Imidazoles -- pharmacology
- In Vitro Techniques
- Losartan
- Male
- Muscle Relaxation -- drug effects
- Muscle Tonus -- drug effects
- Muscle, Smooth, Vascular -- drug effects
- NADH, NADPH Oxidoreductases -- metabolism
- Nitric Oxide Synthase -- antagonists & inhibitors
- Nitroglycerin -- pharmacology
- Norepinephrine -- pharmacology
- Rats
- Rats, Sprague-Dawley
- Superoxide Dismutase -- pharmacology
- Superoxides -- metabolism
- Tetrazoles -- pharmacology
- omega-N-Methylarginine
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Publication Type: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S.
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