Class III antiarrhythmic drugs block HERG, a human cardiac delayed rectifier K+ channel. Open-channel block by methanesulfonanilides. [electronic resource]
Producer: 19960410Description: 499-503 p. digitalISSN:- 0009-7330
- Animals
- Anti-Arrhythmia Agents -- pharmacology
- Benzopyrans -- pharmacology
- Cation Transport Proteins
- Cells, Cultured
- DNA-Binding Proteins
- ERG1 Potassium Channel
- Ether-A-Go-Go Potassium Channels
- Humans
- Ion Channel Gating
- Patch-Clamp Techniques
- Piperidines -- pharmacology
- Potassium Channel Blockers
- Potassium Channels
- Potassium Channels, Voltage-Gated
- Pyridines -- pharmacology
- Trans-Activators
- Transcriptional Regulator ERG
- Xenopus
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
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