Trypanosoma brucei dihydrofolate reductase-thymidylate synthase: gene isolation and expression and characterization of the enzyme. [electronic resource]
Producer: 19960206Description: 11-22 p. digitalISSN:- 0166-6851
- Amino Acid Sequence
- Animals
- Base Sequence
- Enzyme Induction
- Folic Acid Antagonists -- pharmacology
- Genes, Protozoan
- Humans
- Kinetics
- Molecular Sequence Data
- Protozoan Proteins -- antagonists & inhibitors
- Pyrimethamine -- pharmacology
- Recombinant Fusion Proteins -- isolation & purification
- Sequence Alignment
- Sequence Homology, Amino Acid
- Species Specificity
- Tetrahydrofolate Dehydrogenase -- genetics
- Thymidylate Synthase -- antagonists & inhibitors
- Trimethoprim -- pharmacology
- Trypanosoma brucei brucei -- enzymology
- Trypanosoma cruzi -- genetics
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Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
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