Opioid agonist properties of two oxime derivatives of naltrexone, NPC 831 and NPC 836. [electronic resource]
Producer: 19930309Description: 45-50 p. digitalISSN:- 0091-3057
- 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer
- Acetates
- Analgesics -- metabolism
- Animals
- Binding, Competitive
- Bombesin
- Enkephalin, Ala(2)-MePhe(4)-Gly(5)-
- Enkephalin, Leucine-2-Alanine -- metabolism
- Enkephalins -- metabolism
- Guinea Pigs
- Ligands
- Male
- Mice
- Naltrexone -- analogs & derivatives
- Oximes -- pharmacology
- Pain -- chemically induced
- Pyrrolidines -- pharmacology
- Rats
- Rats, Sprague-Dawley
- Reaction Time -- drug effects
- Receptors, Opioid -- drug effects
- Receptors, Opioid, kappa -- drug effects
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Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.
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