Implanted fibroblasts genetically engineered to produce brain-derived neurotrophic factor prevent 1-methyl-4-phenylpyridinium toxicity to dopaminergic neurons in the rat. [electronic resource]
Producer: 19940627Description: 5104-8 p. digitalISSN:- 0027-8424
- 1-Methyl-4-phenylpyridinium -- antagonists & inhibitors
- Animals
- Brain-Derived Neurotrophic Factor
- Cell Line
- Cell Survival
- Cells, Cultured
- Fibroblasts -- metabolism
- Genetic Engineering
- Male
- Nerve Degeneration
- Nerve Growth Factors -- genetics
- Nerve Tissue Proteins -- genetics
- Neurons -- drug effects
- Rats
- Rats, Sprague-Dawley
- Receptors, Dopamine -- drug effects
- Substantia Nigra -- drug effects
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Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.
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