Clinical pharmacodynamics of continuous infusion topotecan in children: systemic exposure predicts hematologic toxicity. [electronic resource]
Producer: 19941010Description: 1946-54 p. digitalISSN:- 0732-183X
- Adolescent
- Antineoplastic Agents -- administration & dosage
- Camptothecin -- administration & dosage
- Child
- Child, Preschool
- Chromatography, High Pressure Liquid
- Female
- Humans
- Infusions, Intravenous -- methods
- Lactones -- pharmacokinetics
- Leukocyte Count -- drug effects
- Male
- Neoplasms -- blood
- Neutrophils
- Platelet Count -- drug effects
- Topotecan
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Publication Type: Clinical Trial; Clinical Trial, Phase I; Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
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