Cleavage of the epidermal growth factor receptor by a membrane-bound leupeptin-sensitive protease active in nonionic detergent lysates of senescent but not young human diploid fibroblasts. [electronic resource]
Producer: 19941005Description: 427-34 p. digitalISSN:- 0021-9541
- Cell Line
- Cell Membrane -- metabolism
- Cellular Senescence
- Detergents
- Diploidy
- Endopeptidases -- metabolism
- ErbB Receptors -- chemistry
- Fibroblasts -- metabolism
- Humans
- Intracellular Membranes -- metabolism
- Leupeptins -- pharmacology
- Ligands
- Phosphorylation
- Protease Inhibitors -- pharmacology
- Protein Processing, Post-Translational
- Solvents -- pharmacology
- Stimulation, Chemical
- Trypsin -- pharmacology
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
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