Differential roles of Glu318 and Thr319 in cytochrome P450 1A2 catalysis supported by NADPH-cytochrome P450 reductase and tert-butyl hydroperoxide. [electronic resource]
Producer: 19940608Description: 397-401 p. digitalISSN:- 0003-9861
- Amino Acid Sequence
- Animals
- Binding Sites
- Catalysis
- Cytochrome P-450 CYP1A2
- Cytochrome P-450 Enzyme System -- biosynthesis
- Glutamates
- Glutamic Acid
- Kinetics
- Microsomes, Liver -- enzymology
- Mutagenesis, Site-Directed
- NADPH-Ferrihemoprotein Reductase -- isolation & purification
- Oxidoreductases -- biosynthesis
- Peroxides -- metabolism
- Rats
- Recombinant Proteins -- biosynthesis
- Saccharomyces cerevisiae
- Threonine
- tert-Butylhydroperoxide
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Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
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