Multifactorial resistance to 5,10-dideazatetrahydrofolic acid in cell lines derived from human lymphoblastic leukemia CCRF-CEM. [electronic resource]
Producer: 19950228Description: 566-73 p. digitalISSN:- 0008-5472
- 5,10-Methylenetetrahydrofolate Reductase (FADH2)
- Acyltransferases -- antagonists & inhibitors
- Antineoplastic Agents -- pharmacology
- Clone Cells
- Drug Resistance
- Folic Acid Antagonists -- pharmacology
- Formate-Tetrahydrofolate Ligase -- metabolism
- Glycine Hydroxymethyltransferase -- metabolism
- Humans
- Hydroxymethyl and Formyl Transferases
- Leukemia, Lymphoid
- Methylenetetrahydrofolate Dehydrogenase (NADP) -- metabolism
- Methylenetetrahydrofolate Reductase (NADPH2)
- Oxidoreductases -- metabolism
- Peptide Synthases -- metabolism
- Phosphoribosylaminoimidazolecarboxamide Formyltransferase
- Phosphoribosylglycinamide Formyltransferase
- Stereoisomerism
- Tetrahydrofolate Dehydrogenase -- metabolism
- Tetrahydrofolates -- pharmacology
- Thymidylate Synthase -- metabolism
- Tumor Cells, Cultured
- gamma-Glutamyl Hydrolase -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
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